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Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues, either by direct growth into adjacent tissue through invasion or by implantation into distant sites by metastasis. Metastasis is defined as the stage in which cancer cells are transported through the bloodstream or lymphatic system. Cancer may affect people at all ages, but risk tends to increase with age. It is one of the leading causes of death in developed countries.

There are many types of cancer. Severity of symptoms depends on the site and character of the malignancy and whether there is metastasis. A definitive diagnosis usually requires the histologic examination of tissue by a pathologist. This tissue is obtained by biopsy or surgery. Most cancers can be treated and some cured, depending on the specific type, location, and stage. Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy. As research develops, treatments are becoming more specific for the type of cancer pathology. Drugs that target specific cancers already exist for several cancers. If untreated, cancers may eventually cause illness and death, though this is not always the case.

The unregulated growth that characterizes cancer is caused by damage to DNA, resulting in mutations to genes that encode for proteins controlling cell division. Many mutation events may be required to transform a normal cell into a malignant cell. These mutations can be caused by chemicals or physical agents called carcinogens, by close exposure to radioactive materials, or by certain viruses that can insert their DNA into the human genome. Mutations occur spontaneously, or are passed down generations as a result of germ line mutations.

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@sarajade_ i wonder what re-treated wood entails....cancer phones for sure
chris_messervey (chris messervey) Tue, 15 Dec 2009 17:24:12 -0000
@sarajade_ i wonder what re-treated wood entails....cancer phones for sure
Overuse CT Scans Lead to New Cancer Cases | Pat's Papers http://retwt.me/1L0NU (via @patkiernan)
TM_Healthcare (Healthcare TweetMeme) Tue, 15 Dec 2009 17:23:58 -0000
Overuse CT Scans Lead to New Cancer Cases | Pat's Papers http://retwt.me/1L0NU (via @patkiernan)
Nanosensors Spot Early Signs of Cancer - http://bit.ly/5qenJF
HealthOC (Health in OC) Tue, 15 Dec 2009 17:23:54 -0000
Nanosensors Spot Early Signs of Cancer - http://bit.ly/5qenJF
RT @cokelogic If you buy a video game for cancer kid this year, check how many hours to finish. Dont want thechild to end before the game
NSRGarret (Garret Martin) Tue, 15 Dec 2009 17:23:51 -0000
RT @cokelogic If you buy a video game for cancer kid this year, check how many hours to finish. Dont want thechild to end before the game
@Ua4a bring awareness to Canine Cancer..wlk across GW Bridge into Manhattan w Luke,Huds & Murph www.2dogs2000miles.org 9am Fri pls rt
rigleytour08 (Di/Rigley) Tue, 15 Dec 2009 17:23:51 -0000
@Ua4a bring awareness to Canine Cancer..wlk across GW Bridge into Manhattan w Luke,Huds & Murph www.2dogs2000miles.org 9am Fri pls rt
@bubblewench Oh I didn't know the breast cancer one was still going on. I clicked til my mouse yelled uncle in Oct
ButifulMess (Beautiful Mess) Tue, 15 Dec 2009 17:23:37 -0000
@bubblewench Oh I didn't know the breast cancer one was still going on. I clicked til my mouse yelled uncle in Oct

 
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Accelerated Partial Breast Irradiation - Details the research study by Stanford University for this treatment method of breast cancer.

Ascent-2: Prostate Cancer Clinical Trial - Gives information for the Novacea Inc. study of the agent DN-101 in combination with Taxotere.
Meta Description: [ Prostate cancer clinical trial information ]

ASSIST-Trials: Ovarian Cancer - Details information on clinical studies for this condition that use the Telik firm's drug-agent TLK286.
Meta Description: [ Ovarian cancer clinical trial information ]

Biomarker Technologies: BT Test - Biotech firm is seeking clinical participants for the evaluation of their blood test to detect breast cancer.
Meta Description: [ Biomarker Technologies offers a method to accurately detect certain biomarkers for breast cancer ]

Breakthrough Generations Study - This UK research inquiry will evaluate over 100,000 subjects to help determine causes of breast cancer.
Meta Description: [ The Breakthrough Generations Study is a major study into the causes of breast cancer. The study will include over 100,000 women in the UK; it plans to be the largest, longest running scientific study of its kind. Breakthrough Breast Cancer, in partnership with The Institute of Cancer Research, is... ]

404 Cancer Trials Support Unit - Information about an NCI-funded program which facilitates participation in phase III clinical trials.

Cancer411 - A interactive resource offering patients and physicians clinical trial information.
Meta Description: [ Comprehensive Cancer Clinical Trials Information ]

CancerAnswers: Breast - Details the working of a clinical trials matching program.

404 CancerBACUP: MSO1 for Mesothelioma - Information presented by a UK non-profit organization about a clinical trial for pleural mesothelioma.
Meta Description: [ Cancerbackup - Europe's leading cancer information service, providing accurate, up-to-date and authorative cancer information, resources and support for people affected by cancer. ]

CancerGuide: Finding Clinical Trials on the Net - Overview guidance as presented by a cancer survivor.

City of Hope: Clinical Trials Online - Search for research programs and current studies at the cancer center in Duarte, California.
Meta Description: [ Clinical Trials On-Line (Clinical Trials Online) describes research programs and ongoing research studies (clinical trials) at City of Hope National Medical Center. ]

CML Vaccine Clinical Trial - Discussion of chronic myelogenous leukemia by the Antigenics firm and its cancer vaccine trial for AG-858.
Meta Description: [ Learn about CML, CML treatments, and an experimental CML vaccine treatment. ]

Coalition of National Cancer Cooperative Groups - Resource for clinical trials and research. Information about experimental anticancer drugs, chemotherapy treatment and cooperative groups.
Meta Description: [ This cancer cooperative group organization provides information about cancer clinical trials, cancer research, patient advocates, drugs for cancer, experimental cancer treatments and general cancer treatment. ]

Criscom International - Outlines the terms and progress of a research study related to cancer risk communication in hereditary breast, ovarian and colorectal cancers.
Meta Description: [ criscom : review the state of knowledge in the field of cancer risk communication, compare the content of cancer genetic consultations, centralize hereditary ovarian cancer information ]

Emerging Med - Provides a clinical trial service matching and referral service for cancer patients. Includes contact details.
Meta Description: [ EmergingMed.com is a matching and referral system designed to simplify your search for clinical trials. ]

EUROCARE - Information about a European study on cancer patients survival and care. Related data files are available for download.
Meta Description: [ Eurocare 3 Survival of cancer patients in Europe ]

FDA: Cancer Clinical Trials Directory - General resource by the U.S. Food and Drug Administration.

GMBTrial: Glioblastoma Multiforme - Phase III clinical study with Transferrin-CRM107 for this type of brain tumor.
Meta Description: [ The Transferrin-CRM107 (Tf-CRM107) Clinical trial is a Phase III clinical study for glioblastoma multiforme. If you or someone you know has been diagnosed with a non-operable, recurrent or progressive GBM tumor, information is now available regarding enrollment in Xenova's international, multi-ce... ]

Hoosier Oncology Group - Evaluates innovative and promising methods and approaches to cancer treatment through clinical studies.

International Cancer Research Portfolio - Allows users to search a database of research projects including clinical trials as supported by major US and UK funding organizations.
Meta Description: [ The ICRP provides a unified database of cancer research supported by leading funding organizations in the US and UK. ]

Irofulven: Prostate Cancer - Phase II clinical trial for hormone-refractory disease by the MGI Pharma company.

Kidney Cancer Vaccine Clinical Trial - Information about the use of Oncophage, an experimental vaccine treatment for this condition by the pharmaceutical firm, Antigenics.
Meta Description: [ Information about kidney cancer, treatment options, clinical trials, and an experimental kidney cancer vaccine ]

Lung Cancer Susceptibility and Outcomes Study - Presents the work of Dr. David Christiani and his team at the Harvard School of Public Health on risk factors and treatment response.
Meta Description: [ The Harvard School of Health Lung Cancer Susceptibility and Outcomes Study. Principle Investigator Dr. David C. Christiani ]

M. D. Anderson Cancer Center: Clinical Trials - Overview information as presented by this Houston, Texas hospital and research complex, as well as listings of ongoing institutional studies.

Melanoma Vaccine: Oncophage - Discussion of melanoma by Antigenics, Inc. in the context of its vaccine therapy trials.
Meta Description: [ Learn about melanoma, melanoma treatments, and an experimental melanoma vaccine treatment. ]

Multi-targeted Therapy.com - Discussion of targeted anti-cancer therapies by Pfizer. Includes links to general information, and to clinical trial data and information.

NCI: Clinical Trials Search - Comprehensive searchable registry presented by the U.S. National Cancer Institute.
Meta Description: [ NCI's gateway to information on cancer clinical trials, including what they are and how they work, how to find ongoing trials, results from recent studies, and resources for cancer researchers conducting trials. ]

Oncolink: Cancer Clinical Trials - General information from this University of Pennsylvania source.
Meta Description: [ OncoLink, the Web's first cancer resource, provides comprehensive information on cancer treatments, cancer research advances, continuing medical education, cancer prevention, and clinical trials. ]

500 Palmetto Research: Breast Cancer - Outlines a current study about the influence of diet and physical activity. Conducted by the University of South Carolina and the Palmetto Health system.
Meta Description: [ We provide information about the different studies conducted by the University of South Carolina together with Palmetto Health about the influence of diet and physical activity on breast cancer ]

Prostate: Acapodene for PIN - This firm is soliciting participants to a Phase II clinical trial with the hormonal agent toremifene for use in prostatic intraepithelial neoplasia which is thought to be a precursor condition to prostate cancer.

Roche: Herceptin Trial - Gives details about the clinical trial involving the use of Herceptin as adjuvant therapy in HER2-positive patients with primary breast cancer. This resource is designed for use by patients and investigators.

Sister Study - Describes a scientific inquiry on the genetic and environmental risk factors for breast cancer.

Siteman: Cervical Cancer Study - Washington University institution seeks patient volunteers for a genetic research project.

Targit Trial - Compares single-day targeted intra-operative radiotherapy to conventional post-operative radiotherapy for breast cancer.

UCSF Comprehensive Cancer Center: Clinical Trials - Description and trials listing related to basic science, clinical research, epidemiology control and patient care programs at this San Francisco, California institution.

404 Us TOO International, Inc - General information as presented by this support organization with links to trial finder services for prostate cancer.

Wales Cancer Trials Network - Gives information on cancer research including current trials, centers, events, meetings, and links.
Meta Description: [ The Wales Cancer Trials Network website provides information on cancer research in Wales, current trials that are up and running, training, events and meetings. It also provides links to useful partner organisations and patient information services. ]

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